求问各位大佬有没有人复现过“Juxtaposition of System Dynamics and Agent-Based Simulation for a Case Study in Immunosenescence”或者“Naive T cells are maintained by thymic output in early ages but by proliferation without phenotypic change after age twenty”这篇文章的?
下面是两个文章链接
https://onlinelibrary.wiley.com/doi/full/10.1046/j.1440-1711.2003.01191.x
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118359
我按照文中的模型和数据复现,仿真软件也相同(AnyLogic&Matlab),但是几种方法建模结果都和论文不同,但我自己的几种方法结果是一致的。
以Naïve T cells from the thymus(scenario4)为例,这是文章给的结果:
我的结果却是下面这样的:
我纵坐标的取值是:
Naive/(Naive+NaiveProliferation+Memory+RealActives(time()))
是我对“percentage CD4+ T cells of a direct thymic origin”理解有误吗,还是其他问题(公式、参数都检查了好几遍了)?