I'm running into this problem where Chrome is responding with the ERR_RESPONSE_HEADERS_TOO_BIG when I try to visit my WordPress instance. I use htop to monitor the server and I see sharp spikes in MySQL and Apache memory consumption as well once the request is made. Finally, if I try to access the site using incognito mode, the site response normally and the error disappear. I looked around and found other related and suggested solutions like LimitRequestFieldSize 4094 and LimitRequestLine 4094 to restrict the header size, but with no luck. My environment is as follows:
WordPress version 4.8
lsb_release -a
No LSB modules are available.
Distributor ID: Ubuntu
Description: Ubuntu 16.04.2 LTS
Release: 16.04
Codename: xenial
uname -r
4.4.0-59-generic
apache2 -v
Server version: Apache/2.4.18 (Ubuntu)
php --version
PHP 7.1.5-1+deb.sury.org~xenial+1