可以参看如下代码，希望有帮助，因为排版原因，可能还需要你调试一下：

Option Explicit

Main()

Sub Main()
  If WScript.Arguments.Count > 0 Then 
      Dim objFSO : Set objFSO = CreateObject("Scripting.FileSystemObject")
      Dim i
      For i = 0 to wscript.arguments.count - 1
          Dim strFilePath : strFilePath = WScript.Arguments.Item(i)
          Dim dirPath : dirPath = objFSO.GetParentFolderName(strFilePath)
          Dim fileBaseName : fileBaseName = objFSO.GetBaseName(strFilePath)
          'WScript.Echo strFilePath
          Dim strNewFileName : strNewFileName = dirPath & "\" & fileBaseName & ".pdf"
          'WScript.Echo strNewFileName
          Dim strFileExt : strFileExt = UCase(objFSO.GetExtensionName(strFilePath))
          Select Case strFileExt
              Case "DOC"
                  DOC2PDF strFilePath, strNewFileName
              Case "XLS"
                  XLS2PDF strFilePath, strNewFileName
              Case "PPT"
                  PPT2PDF strFilePath, strNewFileName
              Case "VSD"
                  VSD2PDF strFilePath, strNewFileName
              Case Else
                  WScript.Echo "Extension Type:  " & strFileExt
          End Select
      Next
  Else
      msgbox("some error")
  End If
End Sub

Sub PPT2PDF(strSourceFile, strDestFile)
  Const ppWindowMinimized = 2
  Const ppWindowNormal = 1
  Const ppSaveAsPDF = 32

  Dim objPPT : Set objPPT = CreateObject("PowerPoint.Application")
  objPPT.Visible = True
  objPPT.WindowState = ppWindowMinimized
  objPPT.Presentations.Open strSourceFile
  objPPT.ActivePresentation.SaveAs strDestFile, ppSaveAsPDF 
  objPPT.Quit()
End Sub

Sub DOC2PDF(strSourceFile, strDestFile)
  Const wdExportAllDocument = 0
  Const wdExportOptimizeForPrint = 0
  Const wdExportDocumentContent = 0
  Const wdExportFormatPDF = 17
  Const wdExportCreateHeadingBookmarks = 1

  Dim objWord : Set objWord = CreateObject("Word.Application")
  Dim objDoc : Set objDoc = objWord.Documents.Open(strSourceFile,,TRUE)    
  objWord.ActiveDocument.ExportAsFixedFormat strDestFile, wdExportFormatPDF, False, _
                  wdExportOptimizeForPrint, wdExportAllDocument,,, _
                  wdExportDocumentContent, False, True, wdExportCreateHeadingBookmarks
  objWord.Quit()
End Sub

Sub XLS2PDF(strSourceFile, strDestFile)
  Const xlTypePDF = 0

  Dim objExcel : Set objExcel = CreateObject("Excel.Application")
  Dim objeDoc : Set objeDoc = objExcel.Workbooks.Open(strSourceFile,,TRUE)    
  objExcel.ActiveWorkbook.ExportAsFixedFormat xlTypePDF, strDestFile
  objExcel.ActiveWorkbook.Close(False)
  objExcel.Quit
End Sub

Sub VSD2PDF(strSourceFile, strDestFile)
  Const xlTypePDF = 1
  Const visOpenRO = 2
  Const visOpenMinimized = 16
  Const visOpenHidden = 64
  Const visOpenMacrosDisabled = 128
  Const visOpenNoWorkspace = 256

  Dim objVisio : Set objVisio = CreateObject("Visio.Application")
  Dim objeDoc : Set objeDoc = objVisio.Documents.OpenEx(strSourceFile, visOpenRO + visOpenMinimized + visOpenHidden + visOpenMacrosDisabled + visOpenNoWorkspace)    
  objeDoc.ExportAsFixedFormat xlTypePDF, strDestFile, 1, 0
  objeDoc.Close
  objVisio.Quit
End Sub

首先visio在不安装插件的情况下不支持直接导出pdf吧。
你可以安装acrobat的pdf打印机设置为默认，然后调用visio 你的文档 /p 打印，生成pdf