SELECT * FROM (
SELECT t1.tid FROM jdp_tb_trade t1
where t1.seller_nick IN ('李心','zhixian50','陈鹏','雪儿','稀饭','婷婷','七七')
and t1.jdp_modified > '2007-11-30 09:52:39'
and t1.jdp_modified <= '2014-04-21 22:31:13'
ORDER BY jdp_modified desc
LIMIT 0,200 ) a inner join jdp_tb_trade b on a.tid = b.tid

给你些参考链接，希望有所帮助：
http://laiguowei2004.blog.163.com/blog/static/36829000201162765456254/
http://www.111cn.net/database/mysql/50921.htm

SELECT t1.jdp_modified,t1.jdp_response FROM jdp_tb_trade t1 where exsits
(SELECT * FROM jdp_tb_trade t2 WHERE ( t2.seller_nick IN ('李心','zhixian50','陈鹏','雪儿','稀饭','婷婷','七七'))
AND ( (t2.jdp_modified > '2007-11-30 09:52:39')
AND (t2.jdp_modified <= '2014-04-21 22:31:13')) and 1.tid=t2.tid ORDER BY t2.jdp_modified desc LIMIT 0,200)

exists

[code="java"]
SELECT t1.jdp_modified,t1.jdp_response FROM jdp_tb_trade t1, jdp_tb_trade t2
where t2.seller_nick IN ('李心','zhixian50','陈鹏','雪儿','稀饭','婷婷','七七') ) AND ( (t2.jdp_modified > '2007-11-30 09:52:39') AND (t2.jdp_modified <= '2014-04-21 22:31:13') ) and t1.tid=t2.tid
ORDER BY t1.jdp_modified desc LIMIT 0,200

[/code]
这样试一下？（主要是把子查询修改为内联查询）

没有必要不要用order by，order by 比较耗时，用exists 性能比in要好一些

是不是没用PreparedStatement？感觉像是头几页mysql生成执行计划，所以慢，后面查询快是因为测试的时候查询条件不变沿用了执行计划，所以快了。换成PreparedStatement+动态参数会不会好点？

你是在搞聚石塔吧，为什么要IN

你为啥不把后面的条件放在前面，可以走索引，缩小范围，然后再查in

我觉得吧这种方式应该可以实现...[url=http://www.baidu.com]展开余下内容[/url]

奇怪哈..既然tid是主键,又是表自连,那直接这样写不就好了?
[code="sql"]
SELECT jdp_modified, jdp_response FROM jdp_tb_trade
WHERE seller_nick IN ('李心','zhixian50','陈鹏','雪儿','稀饭','婷婷','七七')
AND jdp_modified > '2007-11-30 09:52:39'
AND jdp_modified <= '2014-04-21 22:31:13'
ORDER BY jdp_modified desc LIMIT 0,200
[/code]