I'm doing one app which requires AJAX call on almost every user interaction possible, I started writing JS functions, webservices etc. to handle all of that(still long way to go from here).
Now I am wondering If I made a mistake maybe I should put whole page in update panel because I really hate writting JS. Is there some drawback to use it instead of custom written ajax calls to web service and js functions, and is it better to use more update panels or one big?